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- Glossary Term -

Lewy bodies

In terms of their appearance, Lewy bodies are too small to see with the naked eye, but through the lens of a microscope, they typically appear as round bodies surrounded by a lighter halo. Lewy bodies are a buildup of a protein called alpha- synuclein, though the reason that these protein aggregations form in some brain cells and not others is still unclear and a matter of ongoing research. This pathology is involved in dementia with Lewy bodies and Parkinson’s disease dementia.

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